Thursday, January 31, 2013

Want to hop the pond? Europe ?still reasonably priced?

14 hrs.

There's good news for budget-conscious travelers who want to hop the pond to Europe: Two new rankings show many top destinations are downright affordable.

"Most of Europe is still reasonably priced for Americans," with costs in many cities similar to those in North America, said Roger Wade, who researched and compiled two recently released lists that rate 47 major European cities based on affordability.

Bucharest (Romania), Sofia (Bulgaria) and Krakow (Poland) are the cheapest major tourist cities on the European Backpacker Index for 2013, while Zurich (Switzerland), Oslo (Norway) and Venice (Italy) ranked as the most expensive.?

Sofia, Bucharest and Budapest (Hungary) are the most affordable destinations on the Europe 3-Star Traveler Index for 2013, and Zurich, Paris and Venice are costliest.

?In places like Krakow, Budapest, and Prague, it's still very easy to get a meal for $5 and a beer for under $2 -- in very pleasant surroundings,? said Wade, founder of Price of Travel, a website that helps travelers compare expenses in major cities around the world.

Europe's cheapest cities cost about a quarter as much as its most expensive, the indices show.?

The Daily Backpacker Index daily rate for Bucharest is currently $23.38 a day; for Zurich, it?s $119.78 a day.

Sofia is the least expensive city on the 3-Star Traveler Index, due to well-located and well-reviewed hotels that can frequently be found for about $40 per night. A similar 3-star hotel room in Zurich starts at around $155 per night in shoulder season, Wade said. Prices crept up very little overall for food, attractions and transportation, he added.?

Rates for hostels and hotels in some European cities have been declining, data show.

Hostels have come down in Bucharest, Krakow, Zagreb (Croatia), Barcelona (Spain) and even Rome, Wade said. ?It seems like more new hostels continue to open up (often converted from under-performing hotels), and hostel customers tend to be more price sensitive so the expensive places just don't fill up.?

Deals for 3-star hotels are good in St. Petersburg (Russia), Athens (Greece), Berlin and Barcelona, he said. ?The most dramatic difference by far is Moscow, which is 15th cheapest for backpackers, but 34th for 3-star hotels. The city has some good and cheap hostels, and things like public transportation and food are quite cheap if you follow the locals," Wade said. "But international-standard hotels in Moscow are notoriously expensive so it's in a whole different price category for those seeking comfort and English-language menus.??

The Backpacker Index is based on the price of a hostel bed (one night in a good location with good reviews), two public transportation rides, three budget meals, one cultural attraction and three inexpensive beers (or wine) for each day in each city. ?

The 3-Star Index uses a centrally located and well-rated 3-star hotel room, taxi rides and a higher allowance for food prices.

These types of resources "appeal because they intrigue us and speak to the armchair traveler in us all, said Jonathon Day, an assistant professor at Purdue University?s School of Hospitality and Tourism Management.

But they also are practical for planning, to help people organize and sort through an overwhelming amount of information.

It is ?really hard to compare prices of complex things like a visit to a city,? Day said. And by offering new options beyond the iconic locations, which are often expensive, it encourages experimentation. ?Lists like these place destinations that aren't 'top of mind' in front of potential travelers,? he said. ?This is good news for destinations competing for attention ... and ultimately visitors.?

The dollar is at a 13-month low versus the euro, said Neil S. Martin, editor of the Trans-Atlantic newsletter, which reports twice a month on the U.S. market for travel to Europe. ?But that doesn't seem to dissuade very many Americans? from traveling to Europe. U.S. visits to Europe were up 3.9 percent to 11.2 million last year, ? according to the Commerce Department -- probably the best year since 2007, he said.

European countries going through tough economic times -- Greece, Spain, Portugal, Ireland -- are all very pro-tourist and welcoming, he said. The best deals are likely in Hungary, Romania and Bulgaria, "where local currencies have probably dropped versus the dollar."?

But saving money may not be the only benefit of budget travel. ?Rick Steves is famous for saying that the more money you spend, the larger the barrier you create between you and the local people, and I totally agree with that,? said Wade. ?If you have lunch in a cafe on the main town square you'll probably be surrounded by business travelers and other tourists, but if you walk a few blocks in any direction you can probably find the same meal (or better) for half the price and you might be the only foreigner in the place.??

Source: http://www.nbcnews.com/travel/itineraries/most-least-affordable-cities-europe-1B8168002

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Wednesday, January 30, 2013

How the lib media spread phony Sandy Hook ?heckling? story?and how we beat it back (Michellemalkin)

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Texas City: Marathon on track to take over BP refinery on Friday

by T. J. Aulds/ The Daily News

khou.com

Posted on January 28, 2013 at 10:48 AM

TEXAS CITY ? This likely marks the final week that the 475,000-barrel-per-day refinery at 2401 Fifth Ave. South will operate under the BP name. Marathon Petroleum, which purchased the nation?s fourth largest refinery as part of a $2.5 billion deal, is scheduled to take over the 1,200-acre refinery on Friday.

The two companies are expected to finalize the sale of the refinery this week.

Once the deal is closed, Marathon will own two refineries in Texas City ? its existing 80,000-barrel-per-day refinery and BP?s 475,000-barrel-per-day facility.

The new acquisition will be called Marathon Galveston Bay Refinery.

Marathon?s take over ends 14 years of BP?s ownership of the refinery, which it acquired in a merger with Amoco Oil in 1998.

Ray Brooks, who will be the manager of Marathon?s new acquisition, set up his management team; many already are top managers at the Texas City refinery.

Click here to read more at the Galveston County Daily News.

Source: http://www.khou.com/news/neighborhood-news/Texas-City--Marathon-on-track-to-take-over-BP-refinery-on-Friday-188680021.html

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Four Seasons eyes fitness-minded consumers via retreat packages ...

Four Seasons Hotel Cairo at The First Residence

Four Seasons Hotel Cairo at The First Residence is targeting fitness-minded consumers with a special Yoga Retreat package that is hosted by world champion free diver Sara Campbell.

Three retreats by the Egyptian outpost of the Four Seasons are offered during February, March and May that focus on Kundalini yoga that is centered on mind-body connections. Recently the Four Seasons has been promoting more fitness and yoga packages for affluent consumers who want to maintain a healthy lifestyle while traveling.

?We are seeing an increase in hotel packages incorporating both fitness and nutrition, as it is becoming a very popular way to attract additional guests looking for more than just accommodations,? D.M. Banks, director at?DMB Public Relations, New York.

?When hotels bring experts to the property for these specialized retreats, it creates more intrigue and interest surrounding the exclusivity of these packages,? he said.

?When a brand like Four Seasons is internationally known to have incredible spa and fitness facilities in many of their properties, it becomes a Zen location for yoga and meditation retreats.?

Mr. Banks is not affiliated with Four Seasons, but agreed to comment as an industry expert.

Four Seasons Hotel Cairo at The First Residence did not respond by press deadline.

Total package
The yoga that will be practiced on the retreat is Kundalini yoga, which works on the mind-body connection and goes beyond the physical aspect of the poses with emphasis on breathing, meditation, chanting and mudras, a type of yoga that works on hand positions.

The retreat Feb. 28 to March 3 will be hosted by Ms. Campbell, a world-record holding freediver.

The retreat will incorporate daily yoga sessions that include Kundalini yoga, meditation and breathing work. Guests of all levels of yoga practice are able to participate.

The retreat package also includes a three-night stay in a single Superior Room, daily pre-breakfast pranayama and meditation, daily breakfast in Seasons restaurant, three-hour morning workshop, daily lunch, daily afternoon workshops and classes, complimentary 30-minute spa treatment, 35 percent off spa treatments during the duration of the stay and an optional Sadhana practice on the final day.


Superior Room

The package is priced at $1,050 per person.

The property is also offering an additional Yoga Course, which includes the same offers as the package without the accommodation. It is priced at $690 per person.

Since this offer is property specific, the Four Seasons is likely trying to showcase the property and its offerings.

?Four Seasons is leveraging both the property?s location and yoga?s following in development of this unique, experiential campaign,? said Taylor Rains, account coordinator at?Rawle Murdy Associates, Charleston, SC.

?As with most property-specific campaigns, the value for the brand comes with its ability to provide a unique experience,? he said. ?Luxury brands are expected to offer the utmost in high-end amenities, what sets one apart from the next is experience.?

Fitness Buffs
Four Seasons has previously promoted fitness retreats and yoga packages. The brand especially pushed these around New Year?s.

For instance, Four Seasons Resort Marrakech, Morocco, offers detox retreats to entice health-conscious affluent travelers.

The retreats give consumers the chance to engage in activities focused on detoxing the mind, body and spirit. Guests can take advantage of professional nutrition advice, holistic treatments at the spa, detoxification programs, fitness sessions and private yoga sessions while staying at the hotel property (see story).

Also, Four Seasons Hotel Denver is promoting healthy New Year?s resolutions in 2013 with a spa and fitness center membership for local residents.

The membership allows guests to access the spa and fitness center along with a complimentary personal training session, savings on fitness classes, spa treatments and personal training sessions along with other offers. The package is likely targeting locals and those who want a healthy start to 2013 (see story).

?Fitness is absolutely a trend that will continue in the future,? Mr. Rains said. ?It extends well beyond the physical benefits.

?People recognize the importance of healthy living in overall?well-being?and vacations are no exception,? he said.

Final take
Erin Shea, editorial assistant on Luxury Daily, New York?



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Tags: D.M. Banks, DMB Public Relations, events/causes, fitness, Four Seasons, Four Seasons Hotel Cairo at The First Residence, luxury, luxury hotel, luxury marketing, Rawle Murdy Associates, Taylor Rains, travel and hospitality, yoga

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Source: http://www.luxurydaily.com/four-seasons-taps-fitness-minded-consumers-with-retreat-offer/

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Tuesday, January 29, 2013

Consumer Group: The Rich May Pay Less For Car Insurance Even If ...

Driving safely and avoiding accidents isn?t just common sense ? injuries hurt, car wrecks are bad ? but also a way to make sure drivers keep their auto insurance premiums down. But according to figures released by a consumer group recently, insurance companies are in the habit of charging higher premium to safe, low- or moderate-income drivers than to richer people who were at fault for an accident.

The review by the Consumer Federation of America?(via Bloomberg News) says that out of 60 cases it studied, the good drivers were hit with higher prices two-thirds of the time, because of factors like education and occupation. But shouldn?t how well you drive be a pretty important factor?

Yes, according to the CFA, which studied prices in 12 cities from State Farm, Allstate, Geico, Farmers and Progressive. How far one drives and how safe you are doing it?should be how the bar is set, or at least a major part of it.

Using two hypothetical characters the group compared premiums offered to two 30-year-old women. Both had driven for 10 years, lived on the same street in a middle-income Zip code and both wanted the minimum insurance required by whichever state the group was researching.

The imaginary woman who wasn?t married, rented a home, didn?t have coverage for 45 days but has never been in an accident or ticketed with a moving violation was compared to a married executive with a master?s degree who owns her home and has always had continuous insurance coverage. But she?d been in an accident (again, hypothetically) that was her fault and caused $800 in damage within the last three ?years.

The results were somewhat surprising, although there were differences across the five insurers. Farmers, GEICO and Progressive always gave a higher quote to the safer driver than the woman who?d caused an accident. Across all 12 cities in the study, State Farm offered the lowest or second lowest premiums.

?State insurance regulators should require auto insurers to explain why they believe factors such as education and income are better predictors of losses than are at-fault accidents,? said J. Robert Hunter, CFA?s director of insurance and former Texas insurance commissioner.

?Policymakers should ask why auto insurers are permitted to discriminate on the basis of nondriving-related factors such as occupation or education,? he added.

We?re of the same mind. Rewarding good drivers with higher premiums seems like a backwards way to do it. If they?re going to get charged more anyway, where?s the motivation to be a safe driver, beyond insuring your own personal safety?

Largest Auto Insurers Frequently Charge Higher Premiums To Safe Drivers Than Those Responsible For Accidents?[Consumer Federation of America]
Good Drivers With Low Incomes Punished by Insurers [Bloomberg]

Source: http://consumerist.com/2013/01/28/consumer-group-the-rich-may-pay-less-for-car-insurance-even-if-theyre-not-safe-drivers/

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Beyonce Fragrance Launch: Behind the Scenes

Source: http://www.thehollywoodgossip.com/2013/01/beyonce-fragrance-launch-behind-the-scenes/

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No. 2 Notre Dame outlasts No. 9 Lady Vols 77-67

KNOXVILLE, Tenn. (AP) ? One of the best performances of Skylar Diggins' brilliant career spoiled a night when Tennessee was honoring former coach Pat Summitt.

Diggins scored a career-high 33 points Monday as Notre Dame built a 19-point lead and withstood a late Tennessee rally in a 77-67 triumph over the Lady Vols. Notre Dame earned its 14th straight victory and snapped the Lady Vols' nine-game winning streak.

Now the Lady Vols (16-4) hope the loss doesn't prove doubly painful.

Tennessee center Isabelle Harrison was playing Monday with a meniscus injury in her left knee. Harrison hurt the knee again in the first half while driving to the basket, and the 6-foot-3 sophomore had to be helped off the floor. Tennessee coach Holly Warlick had no immediate word on Harrison's condition.

"I hope she's going to be back because we need her," Warlick said. "She's a vital part of our program."

Before the game, Summitt had a banner raised in her honor at Thompson-Boling Arena. Summitt's 1,098-208 career record in 38 seasons gives her the most wins of any Division I men's or women's basketball coach. Summitt stepped down in April after announcing in 2011 that she has early onset dementia, Alzheimer's type.

Summitt's ceremony attracted plenty of star power. The announced crowd of 13,556 included former Lady Vols greats Tamika Catchings, Chamique Holdsclaw, Michelle Marciniak and Candace Parker.

"This is one of the toughest places to play with all those fans out there," Diggins said. "It was a great moment for Coach Summitt, with all those players like Candace Parker and Tamika Catchings on the sidelines. It was a very emotional night tonight, and I thought we did a good job of handling it because they had a lot to play for."

Diggins took over the game early in the first half to put the Irish ahead. She dominated on both ends of the floor again early in the second half. And after Tennessee cut a 19-point deficit to five in the closing minutes, Diggins responded once more.

"She had a phenomenal game. ... She's shooting the ball extremely well," Notre Dame coach Muffet McGraw said. "She shot 50 percent from the field (13 of 26) against a great defense, managed the game, ran the team. Fourth game in nine days, I thought we looked a little tired in stretches at the end, and I really didn't want to take her out to even give her a quick breath. She really gutted it out for 40 minutes with intense pressure on the ball."

Diggins helped Notre Dame (19-1) become the first team to beat both Connecticut and Tennessee in three consecutive seasons. The Irish won 73-72 at Connecticut on Jan. 5.

After losing its first 20 meetings in this series, the Irish beat the Lady Vols in a 2011 regional final and trounced Tennessee 72-44 last season. That 72-44 result represented Tennessee's lowest point total and its second-most lopsided loss in Summitt's 38-year tenure. This marked the first time Notre Dame had beaten Tennessee in Knoxville.

"We went up against a great team and a great player in Skylar Diggins," Warlick said. "We battled. When we learn to maintain a level of play for us, we're going to be very good. We just get in some lulls and some valleys."

Bashaara Graves had 19 points and 13 rebounds for Tennessee. Taber Spani added 12 points and Meighan Simmons had 11 points. Jewell Loyd had 10 points for Notre Dame, while Kayla McBride had nine points and 10 rebounds.

Tennessee used the emotion of the pregame ceremony for Summitt to take an early 7-2 lead, but the Irish answered with a 12-2 run of their own. Diggins scored 11 points in the first 10 minutes of the game to help the Irish build a 33-29 halftime lead.

Diggins was even better early in the second half.

The senior guard scored 12 points in the first seven minutes after the break. She had six points, three steals, one block and an assist during an 11-0 run that gave the Irish a 16-point lead.

"She played great," Spani said. "She played fantastic. She hit shots for them. She was their leader emotionally. She willed their team to victory."

After trailing by as many as 19 points, Tennessee rattled the Irish with a furious rally over the final 10 minutes and cut the lead to 69-64 on Spani's free throw with 3:54 remaining.

That's when Diggins took over again.

She found Madison Cable for a layup that got the Irish out of danger. After Spani and Jasmine Jones missed jumpers on Tennessee's next possession, Diggins sank a 3-pointer to make it a 10-point game.

Notre Dame's lead wouldn't drop below eight again. One of the game's marquee personalities had come through on the big stage once again.

"With all those people out there, it's great for women's basketball," Diggins said. "When you go to college, you dream of playing in games like this."

Source: http://news.yahoo.com/no-2-notre-dame-outlasts-no-9-lady-091303549--spt.html

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THE UFT'S MISSED OPPORTUNITY | Assailed Teacher

One of my favorite historical figures of all time, the great French diplomat Talleyrand. Talleyrand may have been a snake but he had the good sense to know when to do nothing.

One of my favorite historical figures of all time, the great French diplomat Talleyrand. Talleyrand may have been a snake but he had the good sense to know when to do nothing.

New York City is the largest school system in the nation. For the past few weeks the eyes of the education world have been focused on whether or not the city and the union can agree to a new evaluation deal. If they are able to do so, it will be touted as a great ?achievement? for public schools and serve as a model for other school districts around the country.

Contrary to what many of us expected, the round-the-clock negotiations between the city and union two weeks ago was not the endgame. New York State Education Commissioner John King has set a new deadline of February 14 so the city can ?submit?a plan that shows it is prepared to implement large portions of an evaluation system.?

This does not mean the same thing as setting a deadline for the city and union to agree on a plan. King is clearly giving the city a few weeks to turn in a blueprint on what a plan would look like.

It gets confusing right about here:

If the city fails to submit a plan by Feb. 14?that shows it is prepared to implement an evaluation by March 1, King said he has the authority to take over more than $800 million in federal Title I and II funding and withhold more than $300 million in Race to the Top and School Improvement Grants. King said the Title I and II money would still be spent in New York City classrooms, but that he would have control over how it is spent.

Say what? So the blueprint the city must submit by February 14 must show ?it is prepared to implement an evaluation by March 1.? Again, this does not seem to mean the same as having an evaluation in place by March 1, only that the city must show it is ?prepared? to do so.

If not, King says he has the power to take over 800 million dollars of Title I funding for schools and he can outright withhold 300 million dollars. What King intends to do with the 800 million is not clear, although he says it will ?still be spent in New York City classrooms.?

I think they call this ?bluster?. In reality, both February 14 and March 1 can come and go without much happening. The amount of money King can actually withhold (which seems to be around $345 million altogether), is not going to kill us. The 800 million in Title I funding does not seem to be very malleable in King?s hands, despite his threats to ?take control? of it. What can King actually do if the March 1 deadline is not reached? Not a whole lot it seems, at least not now.

Meanwhile, the union wants an evaluation plan to have a sunset of 2 years and Bloomberg wants a plan that will go on indefinitely.?How do the two sides compromise on this?

Bloomberg, never the greatest politician, painted himself into a corner by stating publicly he wanted an indefinite evaluation deal. He cannot now compromise on this because he will look incredibly weak and foolish. That is to say, he cannot compromise on this until the public forgets about it, which would certainly be longer than the March 1 deadline. However, Bloomberg is obsessed with his ?legacy? and what better permanent legacy than a putative evaluation system that finally holds these lazy teachers accountable? Bloomberg will not moderate his stance on this anytime soon.

The union?s president, Michael Mulgrew, holds all the cards here. His agreement to a two-year evaluation deal, which would have been the longest-running in the state, makes him look like a conciliator. The interminable school bus strike?and Bloomberg?s failed negotiations with the CSA?hums in the background as a reminder of Bloomberg?s intractable stance during negotiations in general. King?s comments generally have given Mulgrew cover and corroborated his version of why the negotiations were torpedoed. The mayoral campaign will keep people like Christine Quinn?off of his back for the foreseeable future, lest she wants to lose the ever-important UFT endorsement.

Mulgrew holds all of the cards. He holds all of the cards in the largest school district in the nation. If he had any morals, any conscience, if he cared about the teaching profession at all or cared about the type of precedent any type of evaluation deal would set around the country he would do one thing and one thing only: nothing.

Sure, he might ?talk? here and there with the district about an evaluation but he would have no intention of agreeing to one. Outside of any nominal negotiations, Mulgrew would do absolutely, positively nothing.

February 14 will come and go. March 1 will come and go. June will come and go. The start of the next school year will come and go. King will continue to threaten, to wave his arms, to talk about ?taking control? of funds and he will use every threat in the book to get Mulgrew and Bloomberg to play ball.

And all Mulgrew has to do is nothing.

Bloomberg will not pull back from his demand for a perpetual evaluation regime. He is a lame-duck, a billionaire, a media mogul and he cares not what he does or how he is perceived over the next year. Mulgrew can do nothing with the peace of mind that comes with knowing that Bloomberg will never pull back from the precipice.

So why would Michael Mulgrew, president of the largest teachers? union in the country, do anything?

Perhaps over the summer, after everyone has forgotten about the failed negotiations of a few weeks ago, Bloomberg might moderate his stance on not having any type of sunset clause. He might moderate about some other things as well. He might be so overly obsessed with his ?legacy? that he feels some sort of deal is better than no deal at all. At that point, Mulgrew would be well-served to head back to the negotiating table again with the intention of not coming to an agreement.

After all, how much will Bloomberg moderate his stance? He definitely will want an evaluation system more extreme than anything else in New York State. When negotiations fail, Mulgrew can say again that Bloomberg is being unreasonable by calling for unprecedented and unreasonable reforms. Who is going to call him out? The mayoral candidates? Not likely. King? What can he do? Cuomo? Is Cuomo going to take the side of an increasingly unpopular mayor when he has one eye on the White House?

Mulgrew holds all of the cards and he needs to do nothing. He needs to do nothing to set the first positive precedent to come out of New York City in decades. He needs to do nothing because the backlash to education reform is afoot all across the country, as the Movement of Rank and File Educators has illustrated. He needs to do nothing because it is the right and righteous thing to do. Doing nothing will ensure that the schools of NYC will not become testing factories and the teachers in NYC will not be subject to endless harassment thanks to ?value added? and ?Danielson?. On a nationwide scale, the failure of Race to the Top here in the country?s largest school district would be a black eye on Arne Duncan and his entire effort to ?reform? education.

Unfortunately, teachers here in New York City know that he will eventually do something. He has done something at every stage of this process so far. He was willing to consent to an evaluation framework that made tests the vital part of a teacher?s yearly evaluation. He was willing to agree to an evaluation framework that would see thousands of teachers hauled into 3020a hearings to prove that they are not incompetent. He was willing to accept an evaluation that went on for two years, which is about twice as long as most other school districts in NY State have. He was willing to do these things despite the fact that his teachers? union has no contract. He was willing to do these things despite the fact that what he agreed to was essentially an end-run around tenure rules that his very same union had won for us many moons ago.

In short, us teachers in NYC are too jaded to believe that Mulgrew will not end up caving to the dictates of education deform. This has been his and the rest of UFT leadership?s ?strategy? for many years. There is no sense in believing that anything will change now.

Despite the fact that Mulgrew holds the cards. This despite the fact that he has a long track record to prove that he is not some intractable union hack out to protect ?incompetent? teachers. Despite the fact that doing nothing is the right thing to do in this case, he will end up doing something?and something means disaster.

If the House of Mulgrew does not eventually fall, then the rest of us surely will.

Assail your friends via social media:

Source: http://theassailedteacher.com/2013/01/28/the-ufts-missed-opportunity/

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Early menopause may occur in women with BRCA gene

Jan. 29, 2013 ? Women with harmful mutations in the BRCA gene, which put them at higher risk of developing breast and ovarian cancer, tend to undergo menopause significantly sooner than other women, allowing them an even briefer reproductive window and possibly a higher risk of infertility, according to a study led by researchers at UC San Francisco.

Moreover, the study showed that carriers of the mutation who are heavy smokers enter menopause at an even earlier age than non-smoking women with the mutation.

While the authors note that further research is needed, given the size and demographics of the study, women with the abnormal gene mutation should consider earlier childbearing, and their doctors should encourage them to initiate fertility counseling along with other medical treatments, the scientists said.

The study will be published online in Cancer on January 29, 2013.

This is the first controlled study to explore the association between BRCA1 and BRCA 2 and the age at onset of menopause, the authors said.

"Our findings show that mutation of these genes has been linked to early menopause, which may lead to a higher incidence of infertility,'' said senior author Mitchell Rosen, MD, director of the UCSF Fertility Preservation Center and associate professor in the UCSF Department of Obstetrics, Gynecology and Reproductive Sciences. "This can add to the significant psychological implications of being a BRCA1/2 carrier, and will likely have an impact on reproductive decision-making,'' Rosen said.

Mutations in either of the genes BRCA 1 or BRCA 2 can produce a hereditary, lifetime risk of developing breast cancer and ovarian cancer. Some women decide to reduce their risk by undergoing prophylactic surgery to remove at-risk tissue, including their breasts and ovaries. The abnormal genes are the most identified inherited cause of breast cancer -- carriers are five times more likely to develop breast cancer than those without the mutations, according to the National Cancer Institute.

The new study was designed to determine whether women with the BRCA1 or BRCA2 mutation have an earlier onset of menopause compared with unaffected women.

The researchers looked at nearly 400 female carriers of mutations in the BRCA gene in northern California and compared their onset of menopause to that of 765 women in the same geographic area without the mutation. Most of the women in the study were white because almost all of the BRCA1/2 carriers within the UCSF cancer risk registry are white.

The scientists found that women with the harmful mutation experienced menopause at a significantly younger age -- 50 years -- compared to age 53 for the other midlife women.

Heavy smokers (more than 20 cigarettes a day) with the abnormal gene had an even earlier onset of menopause -- 46 years. By comparison, only seven percent of white women in northern California had undergone menopause by that age, said the authors. Smoking has been shown to alter menstrual cycles and estrogen status, among other impacts.

The authors point out that while their study shows a possible increased risk of infertility for the mutation carriers, further study is needed. They also said that data regarding the age of natural menopause is limited because most women with the mutation are recommended to undergo risk-reducing surgery after they complete childbearing.

"Women with the mutation are faced with challenges in reproductive choices,'' said study co-author Lee-may Chen, MD, a professor in the UCSF Department of Obstetrics, Gynecology and Reproductive Services. "These data may help women understand that their childbearing years may be even more limited by earlier menopause, so that they can make decisions about their reproductive choices and cancer risk-reducing surgery.''

The first author of the study is Wayne T. Lin, MD, MPH, who at the time of the research was a resident at UCSF and is now a fellow at the Brigham and Women's Hospital at Harvard Medical School. Other authors include Marcelle Cedars, MD, a UCSF professor and director of the Division of Reproductive Endocrinology in the Department of Obstetrics, Gynecology and Reproductive Services ; and Mary Beattie, MD, clinical professor in the UCSF Department of Medicine. Study data was collected from the Cancer Risk Program at UCSF and the northern California site of the Study of Women's Health Across the Nation, a project of the University of California Davis and Kaiser Permanente.

Funding for the study was provided by National Institutes of Health grants NR004061, AG012505, AG012535, AG012531, AG012539, AG012546, AG012553, AG012554, and AG012495. Support was also provided by the UCSF Cancer Risk Program Patient Registry, which is supported by the UCSF Helen Diller Family Comprehensive Cancer Center. The Study of Women's Health Across the Nation has grant support from the NIH, Department of Health and Human Services through the National Institute on Aging, the National Institute of Nursing Research, and the NIH Office of Research on Women's Health.

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/FMeGW0Mbx00/130129074429.htm

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Monday, January 28, 2013

Patients' own skin cells are transformed into heart cells to create 'disease in a dish'

Jan. 27, 2013 ? Most patients with an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) don't know they have a problem until they're in their early 20s. The lack of symptoms at younger ages makes it very difficult for researchers to study how ARVD/C evolves or to develop treatments. A new stem cell-based technology created by 2012 Nobel Prize winner Shinya Yamanaka, M.D., Ph.D., helps solve this problem. With this technology, researchers can generate heart muscle cells from a patient's own skin cells. However, these newly made heart cells are mostly immature. That raises questions about whether or not they can be used to mimic a disease that occurs in adulthood.

In a paper published January 27 in Nature, researchers at Sanford-Burnham Medical Research Institute and Johns Hopkins University unveil the first maturation-based "disease in a dish" model for ARVD/C. The model was created using Yamanaka's technology and a new method to mimic maturity by making the cells' metabolism more like that in adult hearts. For that reason, this model is likely more relevant to human ARVD/C than other models and therefore better suited for studying the disease and testing new treatments.

"It's tough to demonstrate that a disease-in-a-dish model is clinically relevant for an adult-onset disease. But we made a key finding here -- we can recapitulate the defects in this disease only when we induce adult-like metabolism. This is an important breakthrough considering that ARVD/C symptoms usually don't arise until young adulthood. Yet the stem cells we're working with are embryonic in nature," said Huei-Sheng Vincent Chen, M.D., Ph.D., associate professor at Sanford-Burnham and senior author of the study.

To establish this model, Chen teamed up with expert ARVD/C cardiologists Daniel Judge, M.D., Joseph Marine, M.D., and Hugh Calkins, M.D., at Johns Hopkins University. Johns Hopkins is home to one of the largest ARVD/C patient registries in the world.

"There is currently no treatment to prevent progression of ARVD/C, a rare disorder that preferentially affects athletes. With this new model, we hope we are now on a path to develop better therapies for this life-threatening disease," said Judge, associate professor and medical director of the Center for Inherited Heart Disease at the Johns Hopkins University School of Medicine.

Disease in a dish

To recreate a person's own unique ARVD/C in the lab, the team first obtained skin samples from ARVD/C patients with certain mutations believed to be involved in the disease. Next they performed Yamanaka's technique: adding a few molecules that dial back the developmental clock on these adult skin cells, producing embryonic-like induced pluripotent stem cells (iPSCs). The researchers then coaxed the iPSCs into producing an unlimited supply of patient-specific heart muscle cells. These heart cells were largely embryonic in nature, but carried along the original patient's genetic mutations.

However, for nearly a year, no matter what they tried, the team couldn't get their ARVD/C heart muscle cells to show any signs of the disease. Without actual signs of adult-onset ARVD/C, these young, patient-specific heart muscle cells were no use for studying the disease or testing new therapeutic drugs.

Speeding up time

Eventually, the team experienced the big "aha!" moment they'd been looking for. They discovered that metabolic maturity is the key to inducing signs of ARVD/C, an adult disease, in their embryonic-like cells. Human fetal heart muscle cells use glucose (sugar) as their primary source of energy. In contrast, adult heart muscle cells prefer using fat for energy production. So Chen's team applied several cocktails to trigger this shift to adult metabolism in their model.

After more trial and error, they discovered that metabolic malfunction is at the core of ARVD/C disease. Moreover, Chen's team tracked down the final piece of puzzle to make patient-specific heart muscle cells behave like sick ARVD/C hearts: the abnormal over-activation of a protein called PPAR?. Scientists previously attributed ARVD/C to a problem in weakened connections between heart muscle cells, which occur only in half of the ARVD/C patients. With the newly established model, they not only replicated this adult-onset disease in a dish, but also presented new potential drug targets for treating ARVD/C.

What's next?

Chen's team was recently awarded a new grant from the California Institute for Regenerative Medicine to create additional iPSC-based ARVD/C models. With more ARVD/C models, they will determine whether or not all (or at least most) patients develop the disease via the same metabolic defects discovered in this current study.

Together with the Johns Hopkins team, Chen also hopes to conduct preclinical studies to find a new therapy for this deadly heart condition.

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The above story is reprinted from materials provided by Sanford-Burnham Medical Research Institute, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Changsung Kim, Johnson Wong, Jianyan Wen, Shirong Wang, Cheng Wang, Sean Spiering, Natalia G. Kan, Sonia Forcales, Pier Lorenzo Puri, Teresa C. Leone, Joseph E. Marine, Hugh Calkins, Daniel P. Kelly, Daniel P. Judge, Huei-Sheng Vincent Chen. Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs. Nature, 2013; DOI: 10.1038/nature11799

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/SopuqUp_z60/130127134201.htm

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Thursday, January 24, 2013

Walters expects to leave hospital soon

NEW YORK (AP) ? Barbara Walters says she expects to be home from the hospital soon after taking a spill at a Saturday night party at the British ambassador's home in Washington.

The veteran ABC newswoman thanked people who expressed concern in a statement read Monday on "The View."

She says she's running a low-grade fever and doctors don't want to release her until her temperature is normal. She says things are going in the right direction and she expects to be home soon.

Her colleagues at "The View" wished her well on the air, although comic Joy Behar couldn't resist a joke.

Behar urged Walters to get well and to "lay off the Grey Goose" vodka.

Source: http://news.yahoo.com/walters-expects-leave-hospital-soon-185635611.html

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Wednesday, January 23, 2013

Benefits of social grooming: Hormone oxytocin facilitates cooperation

Jan. 23, 2013 ? Animals which maintain cooperative relationships show gains in longevity and offspring survival. However, little is known about the cognitive or hormonal mechanisms involved in cooperation. Researchers of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, have now found that cooperative relationships are facilitated by an endocrinological mechanism involving the hormone oxytocin, even when these are between non-kin.

They collected urine samples of 33 chimpanzees from Budongo Forest, Uganda, and measured their urinary oxytocin levels after single episodes of a specific cooperative behavior, mutual grooming. The result: Oxytocin levels were higher after grooming with cooperation partners compared with non-cooperation partners or after no grooming, regardless of genetic relatedness or sexual interest. This suggests that in chimpanzees oxytocin, which acts directly on neural reward and social memory systems, plays a key role maintaining social relations beyond genetic ties and in keeping track of social interactions with multiple individuals over time.

In non-human primates and other social animals strong and enduring social bonds are typically seen between genetically related individuals but also, occasionally, between non-kin, same-sex individuals. Although such relationships are typically defined by high rates of cooperative behaviors, how they are maintained over time is still unclear. In humans and other social mammals the neuropeptide hormone oxytocin plays a central role in facilitating bonding between kin and mating partners. Catherine Crockford, Roman Wittig and colleagues of the Max Planck Institute for Evolutionary Anthropology have now analyzed the role of this hormone in the social relationships between wild chimpanzees.

To this end the researchers observed social interactions ? like mutual grooming ? in a group of wild chimpanzees from Budongo Forest in Uganda and non-invasively collected urine samples of the 33 female and male adult group members on plastic bags or leaves. They determined the level of the hormone oxytocin before and shortly after the animals had been grooming with each other and found that oxytocin levels were especially high in chimpanzees who had been grooming with a ?bond partner?,? a cooperation partner, irrespective of whether this bond partner happened to be their kin or not. On the other hand, the level of urinary oxytocin was much lower in chimpanzees who had been grooming with a ?non-bond partner?, with whom they did not share a cooperative relationship, or in animals who had not been grooming at all. Furthermore, the researchers found that the animal?s sex or age, grooming duration and other factors did not have a significant influence on urinary oxytocin levels.

?Our results demonstrate that a rise in oxytocin was dependent upon the combined effects of social grooming with a bond partner?, says Catherine Crockford of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. ?Crucially, oxytocin levels were similarly high after grooming with non-kin and kin bond partners. This suggests that, in chimpanzees, oxytocin plays a key role in maintaining social relations beyond immediate genetic ties?.

?This is the first study that measures the levels of the hormone oxytocin on wild animals in a non-invasive way?, says Roman Wittig of the Max Planck Institute for Evolutionary Anthropology. ?We have developed a tool with which cross-species comparisons that link underlying physiology and behavior can eventually be made of social mammals in their natural environment?. In future field research this tool will be used to compare single behaviors ? like other cooperative? or aggressive behaviors?by measuring how they differ from each other hormonally.

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The above story is reprinted from materials provided by Max-Planck-Gesellschaft.

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Journal Reference:

  1. C. Crockford, R. M. Wittig, K. Langergraber, T. E. Ziegler, K. Zuberbuhler, T. Deschner. Urinary oxytocin and social bonding in related and unrelated wild chimpanzees. Proceedings of the Royal Society B: Biological Sciences, 2013; 280 (1755): 20122765 DOI: 10.1098/rspb.2012.2765

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/5N7jaS2dzHY/130123094251.htm

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From dark hearts comes the kindness of humankind

Jan. 22, 2013 ? The kind?ness of humankind most likely devel?oped from our more sin?is?ter and self-serving ten?den?cies, accord?ing to Prince?ton Uni?ver?sity and Uni?ver?sity of Ari?zona research that sug?gests society's rules against self?ish?ness are rooted in the very exploita?tion they condemn.

The report in the jour?nal Evo?lu?tion pro?poses that altru?ism -- society's pro?tec?tion of resources and the col?lec?tive good by pun?ish?ing "cheaters" -- did not develop as a reac?tion to avarice. Instead, com?mu?nal dis?avowal of greed orig?i?nated when com?pet?ing self?ish indi?vid?u?als sought to con?trol and can?cel out one another. Over time, the direct efforts of the dom?i?nant fat cats to con?tain a few com?peti?tors evolved into a community-wide desire to guard its own well-being.

The study authors pro?pose that a sys?tem of greed dom?i?nat?ing greed was sim?ply eas?ier for our human ances?tors to man?age. In this way, the work chal?lenges dom?i?nant the?o?ries that self?ish and altru?is?tic social arrange?ments formed inde?pen?dently -- instead the two struc?tures stand as evo?lu?tion?ary phases of group inter?ac?tion, the researchers write.

Sec?ond author Andrew Gallup, a for?mer Prince?ton post?doc?toral researcher in ecol?ogy and evo?lu?tion?ary biol?ogy now a vis?it?ing assis?tant pro?fes?sor of psy?chol?ogy at Bard Col?lege, worked with first author Omar Eldakar, a for?mer Ari?zona post?doc?toral fel?low now a vis?it?ing assis?tant pro?fes?sor of biol?ogy at Ober?lin Col?lege, and William Driscoll, an ecol?ogy and evo?lu?tion?ary biol?ogy doc?toral stu?dent at Arizona.

To test their hypoth?e?sis, the researchers con?structed a sim?u?la?tion model that gauged how a com?mu?nity with?stands a sys?tem built on altru?is?tic pun?ish?ment, or selfish-on-selfish pun?ish?ment. The authors found that altru?ism demands a lot of ini?tial expen?di?ture for the group -- in terms of com?mu?nal time, resources and risk of reprisal from the pun?ished -- as well as advanced lev?els of cog?ni?tion and cooperation.

On the other hand, a con?struct in which a few prof?li?gate play?ers keep like-minded indi?vid?u?als in check involves only those mem?bers of the com?mu?nity -- every?one else can pas?sively enjoy the ben?e?fits of fewer peo?ple tak?ing more than their share. At the same time, the reign?ing indi?vid?u?als enjoy uncon?tested spoils and, in some cases, reverence.

Social orders main?tained by those who bend the rules play out in nature and human his?tory, the authors note: Tree wasps that police hives to make sure that no mem?ber other than the queen lays eggs will often lay illicit eggs them?selves. Can?cer cells will pre?vent other tumors from form?ing. Medieval knights would pil?lage the same civil?ians they read?ily defended from invaders, while neigh?bor?hoods ruled by the Ital?ian Mafia tra?di?tion?ally had the low?est lev?els of crime.

What comes from these arrange?ments, the researchers con?clude, is a sense of order and equal?ity that the group even?tu?ally takes upon itself to enforce, thus giv?ing rise to altruism.

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The above story is reprinted from materials provided by Princeton University. The original article was written by Mor?gan Kelly.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Omar Tonsi Eldakar, Andrew C. Gallup, William Wallace Driscoll. When Hawks Give Rise To Doves: The Evo?lu?tion and Tran?si?tion of Enforce?ment Strate?gies. Evolution, 2013; DOI: 10.1111/evo.12031

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/9pnyaww_fyE/130122143105.htm

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Monday, January 21, 2013

'Twilight' creator Meyer makes Sundance debut

Stephanie Meyer from the film "Austenland," poses for a portrait during the 2013 Sundance Film Festival at the Fender Music Lodge, on Friday, Jan. 19, 2013, in Park City, Utah. (Photo by Victoria Will/Invision/AP Images)

Stephanie Meyer from the film "Austenland," poses for a portrait during the 2013 Sundance Film Festival at the Fender Music Lodge, on Friday, Jan. 19, 2013, in Park City, Utah. (Photo by Victoria Will/Invision/AP Images)

Stephanie Meyer from the film "Austenland," poses for a portrait during the 2013 Sundance Film Festival at the Fender Music Lodge, on Friday, Jan. 19, 2013, in Park City, Utah. (Photo by Victoria Will/Invision/AP Images)

Writer Stephanie Meyer poses at the premiere of "Austenland" during the 2013 Sundance Film Festival on Friday, Jan. 18, 2013 in Park City, Utah. (Photo by Danny Moloshok/Invision/AP)

From left, Bret McKenzie, Jane Seymour, Stephanie Meyer, Jared Hess, Keri Russell and Jerusha Hess attend the Austenland party at Purple Sage during the Sundance Film Festival on Friday, Jan. 18, 2013, in Park City, Utah. (Photo by Benjamin Cohen/Invision/AP)

(AP) ? Stephenie Meyer knows all about obsessive fans. So it makes sense that the "Twilight" author should produce a movie about a woman who takes another writer's work a little too much to heart.

Meyer is a producer on the Sundance Film Festival premiere "Austenland," adapted from her friend Shannon Hale's novel that follows the romantic misadventures of a Jane Austen devotee.

"Austenland" stars Keri Russell as a woman named Jane who is so fanatical about the "Pride and Prejudice" author's fiction that she blows her life savings to visit an Austen-themed British resort. Jane is so fixated on finding her own Austen-style suitor that she has a life-size cut-out of Colin Firth as aloof suitor Mr. Darcy in a BBC production of "Pride and Prejudice."

"I have seen firsthand fanatic fans, passionate people who want to live in that world so badly, who want to be a part of it," Meyer said Saturday in an interview. "I've seen tattoos that scare me to death. I mean, those things are forever. That's not a joke. And I do think people can definitely take that fan love too far. I think it's nice actually to see Jane's journey here, because she realizes this and sort of steps out of it."

"Austenland" marks the directing debut of Jerusha Hess, whose career took off with the 2004 Sundance hit "Napoleon Dynamite," which she co-wrote with her husband, director Jared Hess.

She and Meyer met up through mutual friend Hale. Meyer, who read "Austenland" before it was published, said that she and Hale joked that 10 years down the road, they would get a camera, go to England and make it into a movie themselves.

Hale later met Hess about another film project and mentioned that she and Meyer were dreaming of turning "Austenland" into a movie.

Hess then read "Austenland" and said, "'No, this one's mine. Let's do this,'" said Meyer, who hit it off immediately with Hess. "Jerusha's really lovely and, like Shannon, someone I have a lot in common with. All three of us are moms, and we kind of balance the creative and the real life.

"Jerusha's phenomenally funny and she's just very self-deprecating. She doesn't realize how adorable she is. She's really fun to hang out with."

Hess, whose "Napoleon Dynamite" world was off-kilter, read Hale's novel of Austen zealotry and had her own vision for the film version.

"Let's make it weirder," said Hess, who joked that she instructed production associates to make sure 50 pounds of feathers were in every shot and suggested that the servants' codpieces all be stuffed. A codpiece covered the opening in front of a man's breeches in 16th-century European men's fashion.

"Austenland" co-stars Jennifer Coolidge, JJ Field, Georgia King and Bret McKenzie of the music duo Flight of the Conchords.

While Russell's Jane in "Austenland" is a hopeless romantic, Meyer said she's a very different character from Bella Swan, the love-struck teen played by Kristen Stewart in the five blockbusters adapted from the "Twilight" books.

"Bella isn't like this super fan girl," Meyer said. "Kristen has her own take on it, but for me, Bella is kind of a homebody. She's very practical, and she doesn't get lost in fantasies."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-01-20-Film-Sundance-Stephenie%20Meyer/id-d871e4c7fa8e4ed7a2adf5ba004b642c

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Bloody siege over, de-miners scour plant for traps

Algerian special police unit officers guard the entrance of an hospital located near the gas plant where hostages have been kidnapped by Islamic militants, in Ain Amenas, Saturday, Jan. 19, 2013. Algeria's special forces stormed the natural gas complex in the middle of the Sahara desert in a final assault Saturday, killing 11 militants, but not before they in turn killed seven hostages, the state news agency reported.(AP Photo/Anis Belghoul)

Algerian special police unit officers guard the entrance of an hospital located near the gas plant where hostages have been kidnapped by Islamic militants, in Ain Amenas, Saturday, Jan. 19, 2013. Algeria's special forces stormed the natural gas complex in the middle of the Sahara desert in a final assault Saturday, killing 11 militants, but not before they in turn killed seven hostages, the state news agency reported.(AP Photo/Anis Belghoul)

Norway's Prime Minister Jens Stoltenberg is embraced by Executive Vice President in Statoil, Margrethe Oevrum, Saturday Jan. 19, 2013, after his visit at the drop-in center in Bergen for relatives of the Statoil-employees taken hostage in Algeria. In a bloody finale on Saturday, Algerian special forces stormed a natural gas complex in the Sahara desert to end a four-day standoff with Islamic extremists that left at least 19 hostages and 29 militants dead. With few details emerging from the remote site, it was unclear whether anyone was rescued in the final operation. (AP Photo / Anette Karlsen, NTB scanpix) NORWAY OUT

Two British hostages Peter, left, and Alan, right, (no family name available), are seen after being released, in a street of Ain Amenas, near the gas plant where they have been kidnapped by Islamic militants, Saturday, Jan. 19, 2013. Algeria's special forces stormed the natural gas complex in the middle of the Sahara desert in a final assault Saturday, killing 11 militants, but not before they in turn killed seven hostages, the state news agency reported.(AP Photo/Anis Belghoul)

(AP) ? Algerian de-mining teams were scouring a gas refinery on Sunday that was the scene of a bloody four-day standoff, searching for explosive traps left by the Islamist militants who took dozens of foreigners hostage. The siege left at least 23 captives dead, and the American government warned that there were credible threats of more kidnapping attempts on Westerners.

Algerian special forces stormed the natural gas complex in the Sahara desert on Saturday to end the standoff, and the government said all 32 militants were killed.

The chief government spokesman, Mohamed Said, said Sunday the final toll of hostages killed would be known within hours, but that he "strongly feared it would rise."

He said the militants came from six countries and were armed to cause maximum destruction.

"They had decided to succeed in the operation as planned, to blow up the gas complex and kill all the hostages," Said said.

With few details emerging from the remote site in eastern Algeria, it was unclear whether anyone was rescued in the final operation, but the number of hostages killed on Saturday ? seven ? was how many the militants had said that morning they still had. The government described the toll as provisional and some foreigners remained unaccounted for.

British Prime Minister David Cameron said Sunday three Britons were killed and another three are believed dead, as is a British resident.

"Now of course people will ask questions about the Algerian response to these events, but I would just say that the responsibility for these deaths lies squarely with the terrorists who launched a vicious and cowardly attack," Cameron said.

The siege at Ain Amenas transfixed the world after radical Islamists linked to al-Qaida stormed the complex on Wednesday, which contained hundreds of plant workers from all over the world, then held them hostage surrounded by the Algerian military and its attack helicopters for four tense days that were punctuated with gun battles and dramatic tales of escape.

Algeria's response to the crisis was typical of its history in confronting terrorists, favoring military action over negotiation, which caused an international outcry from countries worried about their citizens. Algerian military forces twice assaulted the two areas where the hostages were being held with minimal apparent mediation ? first on Thursday, then on Saturday.

"To avoid a bloody turn of events in response to the extreme danger of the situation, the army's special forces launched an intervention with efficiency and professionalism to neutralize the terrorist groups that were first trying to flee with the hostages and then blow up the gas facilities," Algeria's Interior Ministry said in a statement about the standoff.

De-mining teams began going through the complex late Saturday and Sunday, searching for explosive traps left behind by the militants, the state news service said, citing security officials that it did not name. Sonatrach, the Algerian state oil company running the Ain Amenas site along with BP and Norway's Statoil, said the entire refinery had been mined.

The State Department issued a travel warning Saturday night for Americans in or traveling to Algeria, citing credible threats of the kidnapping of Western nationals. The department also authorized the departure from Algeria of staff members' families if they choose to leave.

Immediately after the assault, French President Francois Hollande gave his backing to Algeria's tough tactics, saying they were "the most adapted response to the crisis."

"There could be no negotiations" with terrorists, the French media quoted him as saying in the central French city of Tulle.

Hollande said the hostages were "shamefully murdered" by their captors, and he linked the event to France's military operation against al-Qaida-backed rebels in neighboring Mali. "If there was any need to justify our action against terrorism, we would have here, again, an additional argument," he said.

In the final assault, the remaining band of militants killed seven hostages before 11 of them were in turn cut down by the special forces, Algeria's state news agency said. The military launched its Saturday assault to prevent a fire started by the extremists from engulfing the complex and blowing it up, the report added.

A total of 685 Algerian and 107 foreigner workers were freed over the course of the four-day standoff, the Interior Ministry statement said, adding that the group of militants that attacked the remote Saharan natural gas complex consisted of 32 men of various nationalities, including three Algerians and explosives experts.

The military also said it confiscated heavy machine guns, rocket launchers, missiles and grenades attached to suicide belts.

Algeria has fought its own Islamist rebellion since the 1990s, elements of which later declared allegiance to al-Qaida and then set up new groups in the poorly patrolled wastes of the Sahara along the borders of Niger, Mali, Algeria and Libya, where they flourished.

The standoff has put the spotlight on al-Qaida-linked groups that roam these remote areas, threatening vital infrastructure and energy interests. The militants initially said their operation was intended to stop a French attack on Islamist militants in neighboring Mali ? though they later said it was two months in the planning, long before the French intervention.

The militants, who came from a Mali-based al-Qaida splinter group run by an Algerian, attacked the plant Wednesday morning. Armed with heavy machine guns and rocket launchers in four-wheel drive vehicles, they fell on a pair of buses taking foreign workers to the airport. The buses' military escort drove off the attackers in a blaze of gunfire that sent bullets zinging over the heads of crouching workers. A Briton and an Algerian ? probably a security guard ? were killed.

The militants then turned to the vast gas complex, divided between the workers' living quarters and the refinery itself, and seized hostages, the Algerian government said. The gas flowing to the site was cut off.

The accounts of hostages who escaped the standoff showed they faced dangers from both the kidnappers and the military. The militants focused on the foreign workers from the outset, largely leaving alone the hundreds of Algerian workers who were briefly held hostage before being released or escaping.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-01-20-Algeria-Kidnapping/id-1bdfecf3aa574df4a8770f45f3fb09a5

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Thursday, January 17, 2013

Venezuela VP stands in for Chavez before lawmakers

CARACAS, Venezuela (AP) ? Venezuelan Vice President Nicolas Maduro took the place of ailing President Hugo Chavez on Tuesday by delivering a short speech and turning in a state-of-the-nation report amid legal debate about his legitimacy.

Maduro submitted the report in writing from Chavez's government while the president remained in Cuba undergoing treatment after his fourth cancer-related surgery. Opposition politicians argued that the annual speech should have been postponed because the president is supposed to deliver it, and about a dozen walked out in protest.

Maduro announced during the speech, a day after visiting with Chavez in Cuba, that the president designated former vice president Elias Jaua as the new foreign minister. Maduro had kept the foreign minister's post after his appointment as vice president in October.

Opposition leader Henrique Capriles said the naming of Jaua as foreign minister should be reviewed because it was unclear under what authority the vice president was acting when such powers belong to the president alone.

Only a portion of the opposition's representatives walked out of the National Assembly session.

Reflecting critics' charges of heavy Cuban influence in the political events unfolding in Venezuela, one of the legislators who left, Maria Corina Machado said: "The government of Venezuela today is in Cuba, and that's in violation of the constitution."

Oil Minister Rafael Ramirez dismissed the opposition's allegations that the government was acting illegally by going ahead with the special legislative session.

"There's no constitutional controversy," Ramirez told reporters, calling the politicians who walked out "the most extremist sector of the far right."

It was the second time in less than a week that Maduro has presided over an event that would normally have been led by Chavez. Maduro says Chavez remains in charge as president, though it remains unclear when the president might be well enough to address Venezuelans or return home.

"It's declared that they're governing in the name of someone about whom it isn't known for sure how he has been in the past month," said Edgard Gutierrez, a political analyst. "His name is repeated insistently in a huge propaganda operation and a sort of deification, but without it being known whether he will be able to govern again."

Re-elected in October, Chavez has not made any public comments since his latest cancer surgery Dec. 11.

He has been fighting an unspecified type of pelvic cancer, and his long silence has fed speculation about why he hasn't addressed the country by phone on television, as he did during past treatments in Cuba. Government officials have said Chavez is being treated for "respiratory deficiency."

Officials have indefinitely postponed Chavez's inauguration despite complaints by the opposition that the move was unconstitutional.

During last January's the state of the union address, Chavez spoke for nine hours before lawmakers even as he was undergoing cancer treatments.

This year, Maduro spoke for about 15 minutes and turned over to National Assembly President Diosdado Cabello two red books containing the government's annual report.

Maduro cited a clause in the constitution that says the vice president may present reports to the legislature if asked to do so by the president.

"Nicolas didn't come to take the place of the president. He came to bring the documents ... under instructions from the president," Cabello told reporters.

Dozens of Chavez supporters were allowed through the gates into the courtyard of the National Assembly. They cheered for pro-Chavez politicians and chanted: "With Chavez and Maduro, the nation is secure."

Earlier Tuesday, Maduro said Chavez has been making progress in his treatment for a severe respiratory infection and asked questions of his aides during a visit Monday.

Maduro said he and other officials provided Chavez with an update on "the government in a new stage" and other matters.

"He asked our friend Rafael Ramirez about (certain) aspects" of the government, Maduro said in a televised meeting with state governors.

"Our commander is climbing the hill, he's advancing, and that fills us with great happiness," he said.

Maduro made his comments about Chavez's health at a gathering of state governors in Caracas after returning from Cuba along with Ramirez, Cabello and Attorney General Cilia Flores.

Some government foes chafed at a weekend meeting in Havana between Chavez's inner circle and Cuban President Raul Castro. But Maduro, who is thought to have close ties to Cuba's government, dismissed concerns of any undue Cuban influence.

"There are those who say we're a colony of Cuba. It's really an offense against Cuba and against Venezuela," Maduro said.

Three opposition governors attended the meeting led by Maduro on Tuesday morning, including Capriles, who was defeated by Chavez in the presidential election in October. Capriles shook hands with Maduro in a brief exchange at the event.

During Chavez's five-week absence, some Venezuelans have begun speculating about whether his cancer could force him from office and require a new presidential election.

While many of Chavez's followers said they hope he will recover and return home, opposition lawmaker Carlos Ramos said Maduro's repeated appearances in the president's place suggest an effort to promote him as a candidate.

"What I hope is that they call elections soon," Ramos said.

Source: http://news.yahoo.com/venezuela-vp-stands-chavez-lawmakers-013627428.html

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Tuesday, January 15, 2013

Swatch Buys Luxury Brand Harry Winston For $1 Billion - Business ...

GENEVA (AP) ? Switzerland's biggest watch maker, Swatch Group AG, says it has agreed to pay about $1 billion to acquire Canada's Harry Winston watch and jewelry brand.

The Biel, Switzerland-based company says it will pay $750 million to acquire the brand from Toronto-based Harry Winston Diamond Corp. and will also assume as much as $250 million in debt.

The acquisition includes the Harry Winston production company in Geneva and more than 500 employees globally.

Swatch Group's chairwoman, Nayla Hayek, said in a statement Monday that the addition of a jewelry-watch brand "brilliantly complements the prestige segment" of Swatch's portfolio, helping it compete against luxury watch makers.

Harry Winston Diamond Corp.'s chairman, Robert Gannicott, said that his company would change its name to Dominion Diamond Corporation.

The deal is subject to regulatory approval.

Source: http://www.businessinsider.com/swatch-buys-luxury-brand-harry-winston-for-1-billion-2013-1

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Canada to provide transport plane for Mali

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AP

In this August 31, 2012 file photo, fighters from Islamist group Ansar Dine stand guard in Timbuktu, Mali.

Ottawa - Canada will send a military transport plane to provide temporary heavy-lift support for a French campaign against Islamist rebels in Mali, the government said on Monday.

?While the Government of Canada is not, and will not be, considering a direct Canadian military mission in Mali, Canada is prepared ... to provide limited and clearly defined logistical support to assist the forces that are intervening in Mali,? Prime Minister Stephen Harper said in a statement.

Acting on a French request, a giant C-17 cargo aircraft will fly from Canada to France and then on to the Malian capital Bamako, where it will unload, Harper said. The plane will be made available for a week.

Al Qaeda-linked Islamist rebels launched a counteroffensive in Mali on Monday after four days of French air strikes on their northern strongholds.

?(We are) deeply concerned by recent events in Mali. The establishment of a terrorist region in the middle of Africa is of grave concern to the broader international community, including Canada and our close allies,? said Harper.

Canada's appetite for military intervention is low following a five-year mission to Afghanistan, which ended in 2011 after 158 soldiers were killed.

Britain has made available two C-17 transport planes which will ferry French medical gear, tanks and other equipment to Mali this week. - Reuters

Source: http://www.iol.co.za/canada-to-provide-transport-plane-for-mali-1.1451489

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